Rapid specific determination of amniotic fluid lecithins as a test of fetal lung maturity
نویسندگان
چکیده
منابع مشابه
Measurement of "lamellar body phospholipid" in amniotic fluid as a method for assessing fetal lung maturity.
A simple, rapid micro-method, suitable for use in a routine clinical laboratory, is described for isolating a surfactant fraction from 0.1 mL of human amniotic fluid and measuring its phospholipid content. We determined the phospholipid content of this fraction, referred to as "lamellar body phospholipid," in 451 samples of amniotic fluid collected within two days of delivery and related the da...
متن کاملFetal lung maturity in complicated pregnancy, as predicted from microviscosity of amniotic fluid.
We measured the microviscosity of amniotic fluid between 28 and 40 weeks of gestation in 252 normal pregnancies and in 172 pregnancies complicated by factors known to influence fetal lung maturation, including chronic high blood pressure, pregnancy-induced hypertension, diabetes mellitus, and therapy with betamethasone. Comparison of the microviscosity value distributions and regression analysi...
متن کاملFetal lung maturity, as assessed by gas-liquid chromatographic determination of phospholipid palmitic acid in amniotic fluid.
We describe a new and specific method for measurement of lecithin palmitic acid in amniotic fluid. Dipalmitoyl lecithin, the major alveolar surfactant, has previously been estimated by measuring the lecithin-sphingomyelin ratio, total lecithin, total phospholipid phosphorus, and (or) total palmitic acid. Our method is more specific for estimation of dipalmitoyl lecithin, because nonphospholipid...
متن کاملAmniotic fluid fluorescence polarization value at physiological temperature: a marked improvement in assessing fetal lung maturity.
Determination of fetal lung maturity by measurement of the fluorescence polarization (P) value of the amniotic fluid at room temperature has become the method of choice in an increasing number of perinatal units because of its simplicity and relatively high predictive value. Nevertheless, its power to discriminate between cases with and without hyaline membrane disease (HMD) needs improvement. ...
متن کاملAccuracy of amniotic fluid lamellar body counting for evaluating fetal lung maturity.
BACKGROUND Respiratory distress syndrome (RDS) is one of the important causes of mortality in neonates. This study was designed to assess the role of the amniotic fluid lamellar body counting in predicting fetal lung maturity. METHOD This study was conducted during 2010, April to 2011, February, at Isfahan University of Medical Sciences, Isfahan, Iran. One hundred and twenty eight amniotic fl...
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ژورنال
عنوان ژورنال: Journal of Perinatal Medicine
سال: 1973
ISSN: 0300-5577,1619-3997
DOI: 10.1515/jpme.1973.1.3.213